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Current Research

Elizabeth Nash Memorial Fellowship

Richard Moss, M.D., Yael Gernez, M.D., et. al.
CF-ABPA: An Increasing Threat for CF Patients: Clinically relevant tools for diagnosis and monitoring. Stanford University.

Paul Quinton, Ph.D., Ning Yang, M.D., Ph.D., et. al.
Can we correct defective CFTR-induced abnormal mucus in Cystic Fibrosis?
University of California San Diego.

Forest Rohwer, Ph.D., Robert Quinn, Ph.D. et. al.
Identifying Metagenomic Signals Characteristic of Cystic Fibrosis Exacerbation Onset. San Diego State University.

New Horizons Research

Horst Fischer, Ph.D., et. al. Protons, Bicarbonate, and Airway Defense in CF. Children’s Hospital & Research Center at Oakland

Pradeep Singh, M.D., et. al. Bacterial Responses to Antibiotics Within the Lungs of Cystic Fibrosis Patients. University of Washington.

Special Circumstance Awards

Daniel J. Hassett, Ph.D., et. al. Bacteriophage-mediated activation and killing of mucoid Pseudomonas aeruginosa. University of Cincinnati.

Jonathan Widdicombe, Ph.D., et. al. Role of C1 Transport in Secretion of Antimicrobials by Airway Glands. University of California Davis.

Moving Research Forward

As researchers answer questions on the molecular and biochemical mechanisms of CF, more questions follow as the complexity of this disease is encountered. This is why the dedication of CFRI in supporting research is so important.

CFRI’s programs—the Elizabeth Nash Memorial Fellowship and the New Horizons Campaign—have funded research such as Pseudomonas and its interaction with the epithelium, alternate signaling pathways that induce chloride channel function, the role of calcium-activated chloride channels in the lung, antioxidants and the CF lung, mucous gland regulation and secretion, and CF lung microbial populations and their role in susceptibility to infection—all critical issues for CF patients.

The grants we receive are high quality, peer reviewed, and thoughtfully evaluated by Research Advisory Committee members before final funding recommendations are made. My only regret as chair of the RAC is that we don’t have enough funds to support all the proposals we receive.

CFRI Research Advisory Committee
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